FDA approves first non-opioid medicine to help detox

18 May, 2018, 09:27 | Author: Cassandra Gardner
  • The FDA approved a nonopioid drug to assist with opioid withdrawal symptoms as a tool to fight the U.S. opioid crisis

The agency stressed that Lucemyra is not specifically approved for Opioid Use Disorder, and the drug's use shouldn't extend beyond 14 days.

For those addicted to opioids, quitting cold turkey can be a harrowing experience.

Patients who go off opioid painkillers face excruciating withdrawal symptoms such as anxiety, nausea, vomiting, insomnia, muscle aches and more.

Patients usually manage withdrawal symptoms by switching the opioid with another medication or by using therapy.

Dutch Museums Publish 2 Hidden Pages from Anne Frank's Diary
A spokeswoman from the Anne Frank House said the newly discovered text would be available only in Dutch. "Papa has been there". It's believed that the gags were written about three months after her family went into hiding inside the Dutch house.

"The fear of experiencing withdrawal symptoms often prevents those suffering from opioid addiction from seeking help", Gottlieb said in a press release.

Lucemyra suppresses the neurochemical surge that produces the acute and painful symptoms of opioid withdrawal.

Gottlieb also said the FDA will be developing guidance documents for the most efficient path for developing drugs that can be used to treat various types of pain.

Lofexidine is an oral, selective alpha 2-adrenergic receptor agonist that reduces the release of norepinephrine. 866 adults participated in the study. "The lofexidine data demonstrate that, compared with placebo, study participants treated with LUCEMYRA experienced less severe withdrawal symptoms and were significantly more likely to complete opioid withdrawal treatment". Lucemyra isn't a treatment for opioid utilize clutter (OUD), however, can be utilized as a feature of a more extensive, long haul treatment get ready for overseeing OUD.

Little progress made on any Brexit issue
When queried if there was very little progress in recent weeks, he said "a little, not very little". British Science Minister Sam Gyimah told the BBC "we have helped to develop the Galileo system".

Typical patients will receive three tablets taken orally four times a day at five- to six-hour intervals during the period of peak withdrawal symptoms.

On May 16, the Food and Drug Administration (FDA) approved of the first non-opioid treatment for adults suffering from opioid withdrawal symptoms. Reported adverse side effects include low blood pressure or symptoms such as lightheadedness, slow heart rate, dizziness, sleepiness, feeling faint at rest or when standing up, and dry mouth. Some patients received Lucemyra, and some patients received a placebo. Safety and efficacy in patients younger than 17 has not been established, the agency noted. Studies in pediatric patients will include studies of newborns with neonatal opioid withdrawal and studies of different age groups of children who have opioid withdrawal related to stopping medically-prescribed opioid drugs. An advisory committee this March had approved Lucemyra and had advised the FDA accordingly.

As part of a strategy to fight the crisis, the FDA said it's working to decrease opioid exposure to prevent new addictions and punish those who contribute to illicit opioid distribution.

The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices.

Uber Won't Force Sexual Misconduct Survivors Into Arbitration Anymore
The company's revised policies, in addition to not being applied retroactively, also don't apply to class-action claims. The drivers were arrested, are wanted by police, or have been named in civil suits related to the incidents.

Recommended:

  • Hamilton wants to win title with 'perfect' weekends

    Hamilton wants to win title with 'perfect' weekends

    Next up, it's Mercedes who have overcome a slow start to the season to be frontrunners in the constructor's championship. Such was the pace of Hamilton in clean air ahead that by the 15th lap, he had already opened a 6.4-second gap on Vettel.
    Celtics survive 42-point night by LeBron, down Cavaliers 107-94

    Celtics survive 42-point night by LeBron, down Cavaliers 107-94

    With James on the bench, Semi Ojeleye got the line for two and Greg Monroe scored inside for an 11-point lead with 11:14 to go. The sequence lit a fuse that had been dampened by the first-quarter offensive barrage of a clearly motivated LeBron James.
    Man City soak up fans' adulation in victory parade

    Man City soak up fans' adulation in victory parade

    This is a group of players that is still improving and will be hitting the peak years of their career over the next half-a-decade. Ex-Barcelona and Bayern Munich boss Guardiola beat off competition from five other managers to win the prize.
  • Standalone 'Star Wars' film about Lando Calrissian in the works

    Standalone 'Star Wars' film about Lando Calrissian in the works

    Solo's set-up follows that formula, but without the universe-altering mythology of the ancient battle between Jedi and Sith. The video [see below] starts off with a shot of Han ( Alden Ehrenreich ) hanging his lucky dice on a speeder auto .
    Severe weather alert for BI

    Severe weather alert for BI

    Skies will be partly cloudy tonight. "Some of the storms could have some brief, heavy rain and frequent lightning", Reiner said. Much of today's severe weather forecast hinges on continued northward migration of that front.
    US Treasury Sanctions Top Officials At Central Bank Of Iran

    US Treasury Sanctions Top Officials At Central Bank Of Iran

    The United States Treasury imposed sanctions on Tuesday on Valiollah Seif, the governor of the Central Bank of Iran. Trump called the deal unfair and doubted that it would limit the nuclear ambitions of Tehran.
  • Amazon just gave you a Whole Foods reason to get Prime

    Amazon just gave you a Whole Foods reason to get Prime

    Signing up for a free Prime trial is pretty easy, all you need to get started is available at this link. Prime already offers plenty of perks to buyers, on top of the newly added Whole Foods discounts.
    Blake Lively & Ryan Reynolds Make Public Appearance Amid Divorce Rumors

    Blake Lively & Ryan Reynolds Make Public Appearance Amid Divorce Rumors

    Similarly, Brolin is great fun as Cable and there's strong comic support from Dennison, Beetz and a returning T.J. They're joined in this by winning newbie Domino ( Atlanta's Zazie Beetz , who deserves much more screen time).
    Why 'Last Man Standing' was green lit over 'Brooklyn Nine-Nine'

    Why 'Last Man Standing' was green lit over 'Brooklyn Nine-Nine'

    However, he didn't believe the lasting success behind " Last Man Standing " was exclusively based on Baxter's conservative values. Still, Walden stressed that the success of " Roseanne " wasn't the sole factor for giving Allen, 64, the green light.
  • Murphy Brown has a new gig

    Murphy Brown has a new gig

    The final new shows that made the cut for the fall lineup are dramas Federal Bureau of Investigation and God Friended Me . Jay Hernandez ( Suicide Squad ) steps into the role of Thomas Magnum , which was played by Tom Selleck in the original.
    Pep Guardiola named manager of the year

    Pep Guardiola named manager of the year

    When I was a little boy I always say England was a little bit like a paradise. 'Everybody wants to be here. Of course, always I think the records are a outcome of our game, our consistency.
    Reported STDs Reach Record High in California

    Reported STDs Reach Record High in California

    According to the CDC, most people with chlamydia don't have symptoms , or those symptoms may not appear for several weeks. CDPH Director and State Public Health Officer Karen Smith said that STDs can be prevented by consistent use of condoms.


Popular

Three confirmed dead after severe storms in the Northeast
A National Weather Service team will be traveling to Sullivan, New York , on Wednesday, where a possible tornado was reported. CT officials said men in New Fairfield and Danbury were killed Tuesday in separate accidents when trees fell on their trucks.

Europe seeking quick solution to save Iran nuclear deal -Mogherini
European participants in the nuclear deal with Iran should provide within 60 days guarantees on the preservation of the agreement.

Planes warned over ash plume from Hawaii volcano
So far, at least 37 structures - 28 of which are homes - have been destroyed by lava that shot more than 500 feet into the air. But water may not be entering the crater, as feared, and gas and steam may be safely venting, scientists said.

Zuckerberg agrees to face EU Parliament over Facebook data use
Zuckerberg has so far declined to appear, to the British lawmakers' annoyance. Some MEPs will likely be upset by the behind-closed-doors arrangement.

Turkey's President Erdogan wraps up first official United Kingdom visit
Netanyahu described Erdogan as "an expert on terror and slaughter" as a leading supporter of Palestinian Islamist group Hamas. We are talking about. those who have been caught red-handed bearing weapons, those who have been killing people.

Tiger Woods: "I'm not that far off from winning"
And so he did, shooting a 3-under-par 69 to finish in a six-way tie for 11th place, seven shots behind victor Webb Simpson. Not to really mis-hit a shot and only shoot three under par is just weird, because I played much better than that'.

Slain Indiana cop's son greeted by officers on return to school
Two weeks ago, IN police officer Rob Pitt was shot and killed by a homicide suspect during an exchange of gunfire. Christopher Wolfe, 21, was suspected of shooting and killing a 26-year-old man at a home in Terre Haute.

Taliban militants besiege Farah provincial capital in Afghsanistan
Clashes in Farah come amid the Taliban's annual spring offensive , as they vow to target the " American invaders ". Two members of the Afghan forces were killed and four were injured, said Radmanish.

Mahathir, Anwar step in as tensions flare within Malaysia's ruling alliance
There are many faults committed by the previous government, but we can not do everything in one day, so you have to be patient". Mahathir plans to have a small Cabinet of up to 25 members, with at least 10 of the posts filled by next week.

Macron calls friend Trump, angry over his Iran nuclear move
The deal's proponents say it is crucial to forestalling a nuclear Iran and preventing wider war in the Middle East. These questions get at the heart of whether the Iran nuclear deal can continue without the support of the US.